Yintoni i-QuickMice™?
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I-QuickMice ™ ibhekisa kwiimpuku eziveliswe nguI-TurboMice™ubuchwepheshe, kuquka zombini iimpuku ezibubuntu kunye nezinye iimpuku ezichanekileyo ezihleliweyo zofuzo, ezinje ngeKnocked-In (KI), Knocked-Out (KO), kunye neConditional Knocked-out (CKO) iimpuku.Ngaphezu koko, ngeI-TurboMice™Itekhnoloji, inkonzo yethu ye-QuickMice ™ ekhuphisana kakhulu inokubonelela ngamaqhekeza amade eempuku ezihlelwe yimfuza, iimpuku ezihlelwe yimfuza ezininzi, iimpuku zokuvelisa ibhetshi, iimpuku zexabiso eliphezulu, njl.
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I-QuickMice™ ekhawulezayo yokwenza imouse ye-homozygous
Iseli kuthiwa i-homozygous kuhlobo oluthile lwemfuza xa ii-alleles ezifanayo zejini zikhoyo kuzo zombini iichromozomi ezinehomologous.
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I-QuickMice™ ekhawulezayo ukuhlelwa kwemouse eyenziwe ngofuzo
Imifuziselo yempuku eyenziwe ngabantu inoluhlu olubanzi lwezicelo kumacandelo ophando lwe-AIDS, umhlaza, isifo esosulelayo, kunye nesifo segazi.
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I-QuickMice™ ekhawulezayo yokwenza imouse ye-KI
I-Knock-in (KI) bubuchule obusebenzisa ukudityaniswa kwakhona kwe-homologous yemfuza ukuhambisa ijini esebenzayo yangaphandle kulandelelwano lwe-homologous kwiseli kunye ne-genome, kwaye ufumane ukubonakaliswa kakuhle kwiseli emva kokuhlanganiswa kwakhona kwemfuza.
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I-QuickMice™ ekhawulezayo yokwenza imouse ye-CKO
I-Conditional Knock-out (CKO) yitekhnoloji ye-tissue ye-gene yokunkqonkqoza ephunyezwe yinkqubo yokuhlanganiswa kwendawo.
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I-QuickMice™ i-multi-locus gene-edited mouse customization
Ngokufaka isiceloI-TurboMice™itekhnoloji, sinokukhusela ngokuthe ngqo iiseli ze-embryonic stem emva kokuhlelwa kofuzo kwiintsuku ezi-3-5, emva koko sakhe iseli ye-tetraploid, kwaye sifumane i-homozygous multi-locus gene-edited iimpuku kwiinyanga ezi-3-5 emva kokuzalwa kweempuku ezingumama, ezinokugcina unyaka omnye. kubaxumi bethu.
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I-QuickMice™ iqhekeza elide elenziwe ngokwezifiso lwemouse
I-TurboMice™Itekhnoloji yenza kube lula ukuhlelwa kwemfuza okuchanekileyo kwamaqhekeza amade ngaphezulu kwe-20kb, ngaloo ndlela iququzelela ukuveliswa okukhawulezayo kweemodeli ezintsonkothileyo ezinje ngobuntu, i-conditional knockout (CKO), kunye neqhekeza elikhulu le-knock-in (KI).
UkuHamba kweNkonzo
