Iinkcukacha zeMveliso

Iithegi zeMveliso

I-Quickmice™ iqhekeza elide lokwenziwa kweMouse eHlelwe iGene

Ubude bokuhlelwa kwejene ngobuchwepheshe besintu ubukhulu becala bungaphantsi kwe-5kb, kwaye okukhona iqhekeza elihleliweyo lilide lisezantsi izinga lempumelelo.Ngaphezu koko, ukwakha imodeli yegundane elide-elide lokunkqonkqoza / lokunkqonkqoza usebenzisa ubuchule bemveli, iimpuku ze-chimeric kufuneka zikhuliswe kwaye zihlolwe kwizizukulwana ezi-2-3 ukufumana iimpuku ekujoliswe kuzo, kwaye yonke inkqubo ithatha ngaphezu kwe-10- Iinyanga ezili-12.

Iingenelo zohlelo olude lwamaqhekeza emfuza zilele ekukwazini ukoyisa imida ethile yeendlela zemveli zokuhlela.

Isizukulwana esitsha seTekhnoloji yokuLungiselela iMouse eKhawulezayo

I-TurboMice™

Singakunika ngokukhawuleza iimodeli zempuku ezifunekayo ngokusebenzisa itekhnoloji yeTurboMice™ ukuphucula izinga lempumelelo.

Ngokusekwe kweyona nkqubo ilungileyo yokuhlela imfuza ngoosonzululwazi bethu, sinokugqiba ukuhlolwa kweeseli ze-embryonic ezihleliweyo ngaphakathi kweentsuku ezi-3-5, emva koko sakhe i-tetraploid embryo.Emva kwe-surrogacy yomama, iigundane ze-homozygous humanized zingafumaneka kwiinyanga ezi-2-4, ezinokugcina iinyanga ezi-7-8 kubathengi.

I-TurboMice™Itekhnoloji yenza kube lula ukuhlelwa kwemfuza okuchanekileyo kwamaqhekeza amade ngaphezulu kwe-20kb, ngaloo ndlela iququzelela ukuveliswa okukhawulezayo kweemodeli ezintsonkothileyo ezinje ngobuntu, i-conditional knockout (CKO), kunye neqhekeza elikhulu le-knock-in (KI).

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Umxholo weNkonzo

Inombolo yenkonzo. Izalathisi zobugcisa Umxholo wokuhanjiswa Umjikelo wokuhanjiswa
MC005-1 ubude bejini elinye yi-10kb-15kb Akukho ngaphantsi kweempuku ezi-3 eziyindoda 3-4 iinyanga
MC005-2 ubude bejini elinye yi-10kb-15kb Iimpuku ezingama-20 3-5 iinyanga
MC005-3 ubude bejini enye yi-15kb-20kb Akukho ngaphantsi kweempuku ezi-3 eziyindoda 4-5 iinyanga
MC005-4 ubude bejini enye yi-15kb-20kb Iimpuku ezingama-20 4-6 iinyanga
MC005-5 ubude bejini elinye > 20kb Nceda uqhagamshelane nathi

Qhagamshelana nathi

Nceda uqhagamshelane nathi ku:

1) Nceda ukhuphele kwaye ugcwalise le fomu ingezantsi《Ifomu yesicelo sekowuti》, kwaye uyithumele nge-imeyile kuMingCelerOversea@mingceler.com;

2) ITe: +86 181 3873 9432;

3) LinkedIn:https://www.linkedin.com/company/ uthengar/

Ifomu yesicelo sekowuti.docx

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